Old Drug, New Tricks: Existing Medicines Show Promise in Fighting Cancer

The Broad Institute of MIT and Harvard
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PRISM cancer cell viability profiling enables insights into clinical candidate target selectivity: A case study revealing the most selective PRMT5 inhibitors for cancers with MTAP loss – Abstract | Poster
Accelerating the development of biologics: PRISM high throughput screening enables rapid preclinical characterization of antibodies, ADCs and payloads – Abstract | Poster
A cellular platform for systematic comparison of RAS inhibitors using PRISM multiplexed screening – Abstract | Poster