Meet the PRISM Team

Leadership

Jennifer
Roth

Director

Matthew
Rees

Associate Director

Melissa
Ronan

Scientific Operations Manager

Operations

Claudine
Mapa

Project Manager II

Maggie
LeMaitre

Senior Software Project Coordinator

Bailey
Porter

Project Coordinator

Venus
Trent

Senior Administrative Assistant

Research Scientists

Blanche
Ip

Group Leader, Senior Research Scientist

Jacob
Smigiel

Research Scientist II

Colleen
Harrington

Research Scientist II

Laura
Doherty

Research Scientist II

Jill
Eskra

Research Scientist II

Lab Operations & Research Associates

Tenzin
Sangpo

Supervisor, PRISM Cell Operations

Yingsel
Dundutsang

Lab Coordinator

Li
Wang

Technical Lead I

Ellen
Nguyen

Research Associate III

Antonella
Masciotti

Research Associate II

Catherine
Gaitanakis

Research Associate II

Nashielli
Diaz

Research Associate II

Alvin
Kalathungal

Research Associate II

Vivian
Nguyen

Research Associate I

Anthony
Fazio

Research Associate I

Bioautomation & Process Development

Aydin
Golabi

Senior Bioautomation Engineer I

Rachael Barry

Senior Research Associate I

Cole
Ponsi

Bioautomation Specialist I

Ariah
Tucci

Research Associate I

Emily Reeves

Research Associate I

Analytics

Mustafa
Kocak

Computational Scientist II

Ashish
Bino George

Computational Scientist II

John
Davis

Senior Computational Associate

Ursula Widocki

Computational Associate II

Shiker
Nair

Computational Associate I

Software

Jacob
Asiedu

Associate Director, Software

Anup
Jonchhe

Senior Software Engineer

Lia
Petronio

Data Visualization Engineer

Maha
Naim

Software Engineer

Ursula Widocki

Computational Associate II

Ursula is from New Jersey, where she received her BS in Applied Mathematics from The College of New Jersey (TCNJ). She attended the Harvard School of Public Health for her Master’s in Computational Biology and Quantitative Genetics. Ursula’s master’s thesis examined differences of gene regulatory networks of breast cancer subtypes. Before joining PRISM, she studied autoimmune disease networks at Northeastern University as a doctoral student in network science. Outside of work, Ursula enjoys reading books, going to parks, hanging out with friends, playing board games, and visiting museums.

Emily Reeves

Research Associate I

Emily is from Ponte Vedra Beach, Florida which is just outside of Jacksonville. She graduated from Wake Forest University in 2023 where she studied Biochemistry, Spanish, and Ethics while working in an immunology lab focusing on adenoviral replication. As a member of PRISM, Emily works to improve the Amplification and Detection assay and explore the chemistry of cancer targeting molecules. Emily enjoys working out, dancing, and exploring Boston with her friends.

Rachael Barry

Senior Research Associate I

Rachael grew up just south of Boston in Walpole, MA and attended Hobart and William Smith Colleges where she studied biology and geoscience. She worked as a lab tech supporting the biology department and performed paleobiology research with the geoscience department. Prior to PRISM, she worked in Broad’s Genomics Platform doing process development for several library construction workflows, and then moved to a startup for mRNA vaccine quality control. In PRISM, Rachael leads the process development team. Outside of work, she enjoys spending time with friends, golfing, skiing, listening to and playing music, and going on walks!

Anup Jonchhe

Senior Software Engineer
Anup Jonchhe is a Nepali-American from Hornell, NY who studied Biomedical Engineering, minoring in mathematics and computer science, at Rochester Institute of Technology (RIT). At PRISM, he works on automation of data analysis and development of analysis tools, infrastructure, and workflows. Outside work, he enjoys playing and listening to music, playing soccer, and watching the English Premier League.

Shiker Nair

Computational Associate
Shiker is from King of Prussia, Pennsylvania (yes, this is a real place). He received a BS in Biomedical Engineering from Johns Hopkins University with a focus in computational medicine. There, he conducted research in precision care medicine, specifically looking into how data science can be leveraged to create non-invasive, personalized diagnostic tools for patients with cardiac, pulmonary, and neurological conditions. Outside of work, he loves listening to music, learning how to make beats, and organizing game nights.

John Davis

Senior Computational Associate
John is originally from Methuen, MA and now lives in Medford, MA. He earned his BS in Biochemistry from WPI and began his career researching the genetics of aging at UMass Medical School. He started working at the Broad as a member of the CMAP team in 2011 and focused on assay development and scale up using automation. In 2019 he transitioned to a computational role, and now works on data pipelines and analysis. Outside of work, John enjoys hiking and camping, woodworking, and motorcycling.

Mustafa Kocak

Computational Scientist II

Mustafa was born and raised in Istanbul, Turkey. He received a B.Sc. from Bilkent University (Ankara, Turkey) and his Ph.D. in electrical engineering from NYU’s School of Engineering. He joined the Broad as a computational scientist in 2018 and has since been enjoying working as the analytics lead in PRISM. He is interested in machine learning and its applications in bio-statistics. In his free time, he likes to play with his cat, Minder, and reads fiction from all over the world.

Cole Ponsi

Bioautomation Specialist I
Cole grew up in Park Ridge, Illinois. He earned a BS in Bioengineering from Rice University and worked in the Translational Molecular Pathology Immunoprofiling Laboratory at the MD Anderson Cancer Center. He joined the process development team at the PRISM lab in 2022. When not at work, Cole enjoys baseball, hiking, skiing, and playing video and card games with friends.

Vivian Nguyen

Research Associate I
Vivian was born in Cambridge, MA, and grew up in the Greater Boston area. Vivian is a recent graduate from the University of Massachusetts Amherst, earning her BS in Neuroscience. During her undergraduate years, Vivian led an independent research project during which she isolated and identified cytotoxic steroidal glycoalkaloids from lilies. In her free time, Vivian enjoys drawing and adoring her cat.

Aydin Golabi

Senior Bioautomation Engineer I

Aydin was born and raised in sunny Redondo Beach, California, though he spent most of his teenage years traveling around Europe and the Middle East. He earned BS degrees in Physics and Biochemistry from Arizona State University and a Masters in Biomedical Engineering from UC Berkeley. Aydin joined the Broad in 2021, where he develops robotics solutions for improving and scaling the PRISM assay and lab. Outside of science and engineering, Aydin loves music, exploring nature, and spending time with family and friends.

Nashielli Diaz

Research Associate II
Nashielli was born and raised in Berkeley, CA. She graduated in May of 2022 from Tufts University with a B.S. in Biomedical Engineering during which she led research on the impacts of Photodynamic Therapy on the metastasis of Triple Negative Breast Cancer. Nashielli is supporting the R&D team in the PRISM lab. When not in the lab, you can find her crocheting, cooking, and watching Netflix.

Alvin Kalathungal

Research Associate II
Alvin is from Austin, Texas and graduated from The University of Texas at Austin with a Bachelor of Science in Biology with a concentration in Computational Biology and Genetics. His prior research experience revolved around studying the function of DExH box RNA helicases and how the proteins regulate expression. As a member of the PRISM Lab, Alvin will be working with the Cell Culture team. Outside of work, Alvin enjoys reading science fiction novels and geeking out by playing video games and board games.

Catherine Gaitanakis

Research Associate II
Catherine is from Everett, MA. She received her BS in Biochemistry from the University of Massachusetts Boston, where she was a member of the Dowling Research Lab. Catherine joined PRISM in 2021 and is currently working on the Gain of Function project. Outside of work, Catherine enjoys reading, shopping, and spending time with her cats.

Antonella Masciotti

Research Associate II
Antonella is from Lima, Peru, and got her bachelor’s degree in Biotechnology from Rochester Institute of Technology. She joined the PRISM lab under the screening team in 2021. Outside of works she enjoys soccer, surfing and playing with her dog Quentin.

Li Wang

Technical Lead I
Li was born and raised in Beijing, China. She earned her BS in Biotechnology, MS in Microbiology, and a Masters diploma in Japan. She started as a Research Scientist at the Institute of Microbiology at the Chinese Academy of Sciences for 10 years. After moving to Boston, Li worked as a Senior RA at BU, Genetica in DFCI, a Senior RA in the Eric Lander Lab at the Broad, and finally joined PRISM in 2017. She worked on the PRISPR project before joining the Hit Triage team in validating PRISM hit compounds. When not in the lab, Li enjoys traveling, taking in nature and traditional cultures of the world, and sharing her love of pets and gardening with her friends.

Ellen Nguyen

Research Associate III
Ellen is from Winchester, Massachusetts. She received her BS in Biochemistry and Molecular Biology at the University of Massachusetts Amherst and an MS in Molecular and Cell Biology from Brandeis University. At PRISM, Ellen executes the high-throughput screen of collaborator compounds on the PRISM 1000 cell line cell set, as well as works on custom projects. Outside the lab, Ellen likes to hang out with her cats, bake, and crochet.

Yingsel Dundutsang

Lab Coordinator

Yingsel is a Tibetan- American born in India, and raised in Arlington, MA. She studied Biology at the University of Massachusetts Amherst for her undergraduate degree. Before PRISM, she was a Laboratory Assistant in the SQM department at the Broad Institute. As part of the PRISM Team, she helps coordinate the operations of the lab. Outside of work Yingsel greatly enjoys cooking, baking, hiking, and playing tennis.

Jill Eskra

Research Scientist II
Jillian is from Chicago, Illinois. She received her BS in biological sciences and a PhD in pathology from the University of Illinois at Chicago. Jillian came to the Broad Institute in 2022 after completing her postdoctoral training at Johns Hopkins University where she worked on developing noninvasive diagnostic assays for cancer detection and tumor biomarker profiling. As part of the PRISM team, she is involved in research and development of the PRISM technology. Outside of the lab, Jillian enjoys roller skating, dancing the Lindy Hop, and science outreach volunteering as a mentor for STEM students and aspiring scientists.

Tenzin Sangpo

Supervisor, PRISM Cell Operations
Tenzin was born in New Delhi, India but has lived in the Cambridge area since she was nine years old. She went to the University of Massachusetts Amherst for her undergrad and worked as a lab manager and research associate at the Koch Institute for Integrative Cancer Research at MIT before joining PRISM. Tenzin is part of the DMX team working on expanding the cell line models currently available. When she isn’t in the lab, you can find her playing board games and video games with friends. Tenzin loves traveling internationally but hasn’t been able to travel the last few years. She loves cat-sitting for her co-workers and hopes to have a senior cat one day.

Laura Doherty

Research Scientist II

Laura grew up in NC and studied biology and chemistry at UNC-Chapel Hill. She completed her PhD in chemical biology at Harvard University, where she investigated the role of deubiqutinating enzymes in cancer mentored by Sara Buhrlage (Dana-Farber Cancer Institute) and Peter Sorger (Laboratory of Systems Pharmacology and Harvard Medical School). She joined the PRISM team at the Broad in 2021, and her work focuses on leveraging computational analysis and experimental approaches to understand the mechanism of action of novel therapeutic candidates with industry collaborators. Outside of research, she enjoys art, traveling, and reading.

Colleen Harrington

Research Scientist II
Colleen grew up in Baltimore, Maryland and earned her PhD in Cell & Molecular Biology (Cancer Biology program) from The University of Pennsylvania. Colleen joined PRISM in 2020 where, as part of the target deconvolution team, she works to elucidate the molecular targets of interesting compounds screened in PRISM with the goal of advancing the best candidates to drug discovery programs. Outside of the lab, she enjoys getting outdoors on the many ski slopes, hiking trails, and beaches of New England.

Jacob Smigiel

Research Scientist II
While spending time moving around as a young kid, Jacob most often calls the mountains of Colorado home. Jacob received a BS in Cell & Molecular Biology at John Carroll University and a Ph.D from Case Western Reserve University. During his Ph.D. and post-doc, he studied how cytokines in the tumor micro-environment can bolster metastatic and tumor initiating properties. Jacob currently works on new screening approaches with the PRISM cell set, including 3-D formats, new media compositions, and drug resistance profiling. When not in the lab you’ll often find Jacob cooking or trekking a few mountains with his camera in tow.

Blanche Ip

Group Leader, Senior Research Scientist
Blanche received her M.S. and Ph.D. in Biochemical and Molecular Nutrition at Tufts University, where she investigated the connections between obesity and liver cancer. She completed her postdoctoral training at Boston University in immunometabolism, and at Brown University in bioengineering. She was an Assistant Professor (Research) at Brown University before joining the PRISM team in 2022. As a PRISM Assay Development Senior Research Scientist, Blanche supports the PRISM R&D efforts through planning and execution, writing grant proposals, and mentoring junior members of the team. Edible chemistry (baking) is Blanche’s other passion, along with traveling, hiking and photography.

Venus Trent

Senior Administrative Assistant
Venus is from Dorchester, Massachusetts. She studied Sociology at the University of Massachusetts, Boston, and received her Master’s in Business Administration with a concentration in Human Resources at Keller Graduate School of Management in Midtown, New York. Venus joined PRISM in 2022 and supports the team’s administrative needs. Outside of work, Venus enjoys photography, playing basketball, playing UNO flip, going to the movies, eating good food, and spending time with her daughter.

Bailey Porter

Project Coordinator
Bailey was born and raised in Kansas City, where he earned a Bachelor’s in Medical Biochemistry with minors in Anthropology and Leadership Studies from Kansas State University. After graduating, he worked as an admissions officer for his alma mater before moving to Boston in the summer of 2020 to transition into the biotech space. Bailey worked in recruiting and employee experience for Relay Therapeutics in Cambridge, MA before joining the PRISM team as a Project Coordinator in March 2022. He is excited to leverage his people experience in this new role to begin building his project management skills and drive forward impactful science. Outside of work, Bailey enjoys exploring new places, anything food, dancing, and (trying to) take care of his plants.

Leva Blackwell

Operations Specialist
Leva grew up in Southern Maine and graduated with a BS in Psychology and Public Health from the University of Massachusetts in Amherst. She has spent the last few years working in higher education. Leva joined PRISM in late 2021 and supports the administrative and operational needs of the team. Outside of work, Leva loves spending time with family and friends, cooking Persian food, playing board games, and watching movies.

Maggie LeMaitre

Senior Software Project Coordinator

Maggie grew up just outside of Boston in West Newbury, MA (otherwise known as the hometown of John Cena). She studied at the University of Richmond and Suffolk University, graduating with a BA in Political Science. Before coming to the Broad, Maggie served as an Account Manager and then Operations Lead for a software startup. Aside from work, Maggie enjoys boating, Netflix, chicken fingers, and coffee.

Claudine Mapa

Project Manager II
Claudine was born in Manila, Philippines, and grew up on the south shore of Massachusetts. Claudine holds degrees in biochemistry and molecular biology (B.S. University of Massachusetts Amherst) and biomedical sciences (Ph.D. University of Massachusetts Chan Medical School). She completed her postdoctoral training in preclinical drug development at Boston Pharmaceuticals before joining the PRISM team in 2020. As the PRISM project manager, she develops project plans, coordinates logistics and finances, and monitors the execution of collaborations and R&D projects. Outside of work, she enjoys hiking, rock climbing, and skiing.

Brienne Engel

Alliance Manager
Brienne grew up in the Upstate New York town of East Greenbush. She holds degrees in biochemistry (B.S. Brandeis University), biological oceanography (M.S. University of South Florida), and cancer biology (Ph.D. Moffitt Cancer Center). She joined the PRISM team in 2020 and as the team’s alliance manager, Brienne helps plan and execute collaborations. She is a great point of contact for information about the PRISM assay and how we work with outside groups. Outside of work, Brienne is an avid rock climber, aerial circus artist, and Latin dancer.

Melissa Ronan

Scientific Operations Manager
Melissa grew up in the suburbs of New Jersey. She earned her BA in Psychology from Rutgers University and her Masters in Biomedical Sciences from UMDNJ, with a focus in Pharmacological Sciences. She’s been at the Broad since 2018. As the PRISM Screening Lead, she plans and coordinates all PRISM screens, both large and small, for internal as well as external collaborators. In her free time, Melissa likes reading, cooking, traveling, and spending time outdoors.

Matthew Rees

Associate Director

Matthew was born and raised in Blacksburg, Virginia. He obtained his bachelor’s degree, a masters in biochemistry, and a DPhil in clinical medicine at the University of Oxford as a participant in the National Institutes of Health/University of Oxford IRTA fellowship program. Matthew joined the PRISM team in 2019 and works on understanding the targets and mechanisms of action of new potential cancer therapeutics identified using PRISM, as well as research & development for the PRISM technology.

Luc de Waal

Group Leader, Research Scientist

Originally from the quaint town of Culemborg in the Netherlands, Luc arrived in Boston in 2010 after graduating from the Biomedical Sciences program at the University of Utrecht and completing his PhD in the Matthew Meyerson lab at the Dana-Farber Cancer Institute. In PRISM, Luc’s team works on identifying compounds that have interesting killing profiles in the PRISM screen. They subsequently try to identify the target of these compounds and aim to advance some of them into a drug discovery program, with the final goal of helping cancer patients. When not at work, Luc enjoys activities that are relaxing and rewarding including woodworking, cooking, reading, and playing board games.

Jennifer Roth

Director
Jen is a New England Native from Old Lyme, CT. Jen earned a BS in biochemistry from the University of New Hampshire, an MBA from Boston University, and a Master’s in Biology from Brown University. Jen is responsible for leading the amazing PRISM team. She joined the Broad in 2014, and built the PRISM team and platform of almost 1000 cell lines in a short amount of time. Jen’s role as the Director has her planning and strategizing for the entire team. She directs large pharmaceutical projects and dozens of internal and external collaborator projects. Outside of work, Jen enjoys cooking, spending time with her family, and skiing.

Jacob Asiedu

Associate Director, Software
Jacob joined the Broad Institute over 10 years ago, spending most of that time as Associate Director of Software for the Connectivity Map. He has been with the PRISM Team for 3 years as the Associate Director of Software.

Ashish George

Computational Scientist II
Ashish is from Cochin, a city in tropical, south-Indian state of Kerala. He received his undergraduate degree from IIT-Madras before moving to Boston for a PhD in physics. During his PhD and postdoc, Ashish employed mathematical modeling and computational data analysis to understand complex microbial populations. He joined the PRISM analytics team in 2023 to develop and execute new data analysis strategies and predictive models that further PRISM team goals. Outside of work, he loves exploring new places and foods, playing board games, and reading.

Ariah Tucci

Research Associate I
Ariah is a research associate on the PRISM Amp and Detect team. She graduated from UMass Amherst and received a Bachelor’s in Microbiology, and during her time in college, she was able to get a variety of research experience in fruit fly genetics, plant pathology, and soil biochemistry. She previously worked at a biotech startup working on cellular agriculture, where she was a research and operations associate. Aside from work, Ariah loves dogs, plants, reading, hiking, and music.

Nathaniel Dale

Process Development Associate
Nate currently lives in Bellingham, MA, but mainly grew up in Roxbury, Boston. His background is in biology with a concentration in biochemistry and while at Emmanuel College, he delved into understanding DNA- protein binding interactions, a major component in DNA repair mechanism. In PRISM, Nate helps the process development team by looking for ways to automate and help integrate into a robust high-throughput within the PRISM assay. In his spare time, he loves spending time with his daughter, Natalynn. Together, they enjoy reading, painting and looking at the sky!

Anthony Fazio

Research Associate I
Tony is originally from Long Island, NY. He received his B.S in Microbiology from UMass Amherst in 2021. As a member of PRISM, Tony currently works on the Cell Team. Outside of work, he enjoys cooking, playing board/card games, reading and going to the movies.

Maha Naim

Software Engineer
Maha was born and raised in South Florida. Before joining PRISM, she earned her B.S. in Biology and Behavioral Neuroscience from Nova Southeastern University and her M.S. in Bioinformatics from Boston University. In her free time, Maha enjoys spending time outdoors, trying new boba spots, writing, and film photography.

Lia Petronio

Data Visualization Engineer
Lia grew up in New Jersey where she earned a Bachelor’s in Fine Arts from Rutgers University. She moved to Boston for a Master’s in Fine Arts in Information Design and Visualization at Northeastern University. After graduating, Lia worked in Northeastern’s Communications Department and taught courses on design and web-development. A few years later, with a desire to get closer to biological research and data, she came to Broad Institute as a Data Visualization Engineer, working on the Pattern Team prior to joining PRISM at the start of 2023. She is currently focused on designing and developing a web-based portal for exploring PRISM compound screening data through interactive visualizations and is passionate about finding new ways to visualize complex data by leveraging visual perception and math. In her free time, Lia makes collages, videos, and other art, goes for long walks, rides her OneWheel, and skateboards.

Bruce Boring

Senior Manager of Finance & Operations
Bruce was born and raised in Boston, Massachusetts. He attended Suffolk University where he would earn his B.S. in Biology. Before joining PRISM in early 2023, he was an Operations Manager for the Metabolomics Platform and prior to that he was a Research Administrator in the Office for Sponsored Research at the Broad Institute. As the Senior Manager of Finance and Operations, he works with the Director of PRISM and the leadership team to develop and execute our strategy, works to develop and continuously improve our team culture, and manages all of PRISM’s finances. Outside of work he enjoys traveling, cooking, gardening, gaming, and spending time with his family.